Collagen drops

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Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 27x27 mkm; Points number is 300x300; Left image - topography. Right upper image - phase.

Right lower image - topography 3D.


Collagen drops on surfase. AFM image. Topography 3D

Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 19x19 mkm; Points number is 300x300. Left image - topography. Right upper image - phase.

Right lower image - topography 3D.

Collagen drops on surfase. AFM image. Topography 3D

Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 40x35 mkm; Points number is 300x300. Left image - topography. Right upper image - phase.

Right lower image - topography 3D.

Collagen drops on surfase. AFM image. Topography 3D

Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 30x30 mkm; Points number is 300x300. Left image - topography. Right upper image - phase.

Right lower image - topography 3D.

Collagen drops on surfase. AFM image. Topography 3D

Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 63x46 mkm; Points number is 300x300. Left image - topography. Right upper image - phase.

Right lower image - topography 3D.


Collagen drops on surfase. AFM image. Topography 3D

Collagen drops on surfase. AFM image. Topography.

Collagen drops on surfase. AFM image. Phase.

Drops of collagen on silicon wafer deposited by bioprinting. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Image size 50x50 mkm; Points number is 300x300. Left image - topography. Right upper image - phase.

Right lower image - topography 3D.


Collagen drops on surfase. AFM image. Topography 3D

Drops of collagen on silicon wafer deposited by bioprinting. Images courtesy of Institute of transplantology and artificial organs, Moscow. Images was obtained with scanning probe microscope Certus Standard. Semi-contact mode.

Bio-printing - the creation of biomaterials, parts of biological tissues and whole organs using the technology of printing. In general, the process of such devices (devices for printing biological materials) recalls the work of an inkjet printer.However, unlike the conventional printer, such a device can create three-dimensional objects (see 3D-printer).

As a material for printing can be used by various biomaterials, both organic and inorganic bio-compatible, individual living cells. The use of different cartridges or several nozzles allows print several types of cells and materials.

Currently, Bio-printing technology is in its early development as well as working out of this technology requires considerable time and effort. During the creation of such technology is necessary to study the behavior of biological materials in print, their interaction with the substrate and already printed layers. One tool for such studies is the scanning probe microscope, which allows to study the behavior of droplets and individual cells on the surface after printing.

Collagen (from the Greek Kolla - glue, genes - giving birth, is born. See Collagen) - fibrous protein that forms the basis of connective tissues (tendon, bone, cartilage, dermis, etc.) and ensuring its strength and elasticity . Currently used for the creation of artificial skin substitutes used in the treatment of burns. Perspective is the creation of implants included this protein.

 

Полистирольные сферы

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Латексные сферы   покрытые пленкой воды, АСМ изображение. Режим "фазы".

 

 

 

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